Ranibizumab in Patients With Branch Retinal Vein Occlusion
Status:
Completed
Trial end date:
2009-12-01
Target enrollment:
Participant gender:
Summary
In a recent study we could show that the early retinal venous vasoconstriction after grid
photocoagulation in branch retinal vein occlusion (BRVO) is closely correlated to the visual
outcome after three months. This could be of clinical importance, because the degree of
vasoconstriction might be an early marker of treatment success, compatible with the idea that
hypoxia is the major trigger of VEGF in BRVO. The present study evaluates the response of
retinal vessel diameters to anti VEGF treatment with lucentis in patients with BRVO. This is
done in an effort to gain insight into the retinal hemodynamic consequences of anti VEGF
treatment in BRVO. The hypothesis that anti VEGF treatment is associated with a
vasoconstrictor response in retinal vessel in patients with BRVO is tested.