Ranibizumab for Neurofibromas Associated With Neurofibromatosis 1
Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to determine if ranibizumab can prevent the growth of
neurofibromas. We will also be collecting extra blood and serum samples to help us learn more
about NF1. Ranibizumab is a drug that affects the development of blood vessels that feed
tumors. It targets a substance in the body called VEGF (Vascular Endothelial Growth Factor).
VEGF helps tumors to grow and survive by supporting the growth of blood vessels that bring
nutrients to the tumor. VEGF is made by cancerous tumors and also by non-cancerous tumors
such as neurofibromas.