Randomized Trial of Two Analgesics in Elderly ED Patients

• Status: Not yet recruiting
• Trial end date: 2024-07-30
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to perform a randomized, double blind 2-arm clinical trial of the comparative efficacy of 2 oral analgesics in the the management of acute pain in elderly patients who present and then are discharged from the ED.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Albany Medical College; Montefiore Medical Center
• Treatments: Acetaminophen; Acetaminophen, hydrocodone drug combination; Analgesics; Codeine; Hydrocodone; Ibuprofen; Oxycodone

Criteria

Inclusion Criteria:

• Complaint of acute pain of < 7 days duration

• ED attending plans to discharge patient home with an oral analgesic

Exclusion Criteria:

• Inability to confirm reliable means of phone followup.

• Past use of methadone

• Chronic condition requiring frequent pain management such as sickle cell disease, fibromyalgia, or any neuropathy

• History of an adverse reaction to any of the study medications

• Ibuprofen or acetaminophen or opioids taken in past 4 hours

• History of peptic ulcer disease

• Report of any prior use of recreational narcotics

• Medical condition that might affect metabolism of opioid analgesics, acetaminophen, or ibuprofen such as hepatitis, renal insufficiency, hypo- or hyperthyroidism, Addison's or Cushing's disease