Overview

Randomized Trial of NSAID vs Placebo Prior to Ureteral Stent Removal

Status:
Completed
Trial end date:
2020-01-11
Target enrollment:
0
Participant gender:
All
Summary
This study plans to learn more about whether ibuprofen can reduce pain after removal of a ureteral stent more than a placebo. Some patients experience pain after removal of a ureteral stent. The investigators plan to learn how often this occurs and whether it can be prevented. The investigators hypothesize that children who have a temporary, indwelling ureteral stent will experience a significantly less post-operative pain if given a non-steroidal anti-inflammatory (NSAID) prior to removal of the ureteral stent when compared to placebo. The investigators hypothesize that the incidence of severe post-stent removal pain is similar to an adult population.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
University of Colorado, Denver
Collaborator:
Children's Hospital Colorado
Treatments:
Ibuprofen
Criteria
Inclusion Criteria:

- ages 4-17

- unilateral ureteral stent placed after ureteropelvic junction obstruction repair or
treatment of upper tract urolithiasis

Exclusion Criteria:

- bilateral stents

- undergoing other concomitant procedure at time of planned ureteral stent removal

- indication for stent other than ureteropelvic junction obstruction repair or treatment
of upper tract urolithiasis

- pregnant

- developmental delay

- allergy to ibuprofen or non-steroidal anti-inflammatory medication class

- chronic kidney disease

- prior renal transplant

- history of nasal polyps

- history of asthma