Overview

Randomized Trial of Avelumab-cetuximab-radiotherapy Versus SOCs in LA SCCHN (REACH)

Status:
Active, not recruiting
Trial end date:
2027-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to demonstrate that treatment with avelumab in combination with RT-cetuximab is superior to standard of care (SOC) cisplatin-RT and/or to SOC RT-cetuximab alone in terms of progression-free survival (PFS) in front-line patients with locally advanced SCCHN.
Phase:
Phase 3
Details
Lead Sponsor:
Groupe Oncologie Radiotherapie Tete et Cou
Collaborators:
Merck Sharp & Dohme Corp.
Pfizer
UNICANCER
Treatments:
Avelumab
Cetuximab
Cisplatin