Randomized Study of Spinal Anesthesia Compared With Traditional Epidural Anesthesia Concerning Peroperative and Postoperative Pain After Open Nephrectomy in Patients With Renal Cell Carcinoma

• Status: Completed
• Trial end date: 2015-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The study aim to study whether spinal anesthesia (using: bupivacain, morfin och klonidin) can be better than epidural anesthesia during and after open surgery for renal cell carcinoma. Per- and postoperative pain after spinal anesthesia with klonidin can be reduced and, thus, shorten the hospital stay and rehabilitation of the patients.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Umeå University
• Collaborator: University Hospital, Umeå
• Treatments: Anesthetics; Bupivacaine; Clonidine

Criteria

Inclusion Criteria:

• all patients in ASA score I - III, planned to be treated with open radical nephrectomy or nephron-sparing surgery having renal cell carcinoma

Exclusion Criteria:

• patients in ASA score IV-V,

• patients with advanced tumour thrombus in vena cava inferior,

• patients with high risk for bleeding

• patients with previous chronic pain symptoms

• patients having drug abuse

• patients having cognitive deficiencies or dementia disease

• patients with any contraindication of either spinal or epidural anesthesia

• patients younger than 18 years and pregnant woman

• patients having a weight less than 45 kg or weight over 120 kg