Overview
Randomized Study of Midodrine, an Alpha Adrenergic Agonist, in Patients With Neurally Mediated Syncope
Status:
Completed
Completed
Trial end date:
1969-12-31
1969-12-31
Target enrollment:
0
0
Participant gender:
All
All
Summary
OBJECTIVES: Determine the efficacy of midodrine, a selective alpha 1 adrenergic agonist, in preventing neurally mediated syncope.Phase:
N/AAccepts Healthy Volunteers?
NoDetails
Lead Sponsor:
Icahn School of Medicine at Mount SinaiTreatments:
Adrenergic Agonists
Midodrine
Criteria
PROTOCOL ENTRY CRITERIA:--Disease Characteristics-- Diagnosis of neurally mediated syncope (vasovagal fainting)
Sudden fall in blood pressure AND Slowing of the heart AND Temporary loss of consciousness
AND Hemodynamic response to head up tilt --Prior/Concurrent Therapy-- No other concurrent
adrenergic agonist or antiagonist --Patient Characteristics-- Fertile patients must use
effective birth control