Randomized Placebo-Controlled Study of Aerobic Exercise and Resistance Training Plus Megestrol Acetate for HIV-Wasting
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
OBJECTIVES: I. Evaluate the effect of aerobic exercise and progressive resistance plus
megestrol acetate on lean body mass of patients with human immunodeficiency virus-related
weight loss (HIV-wasting).
II. Evaluate whether exercise acutely alters immune function. III. Evaluate whether long-term
exercise improves immunocompetence. IV. Evaluate the accuracy of multifrequency bioelectrical
impedance spectral analysis in measuring body composition.
V. Assess the impact of these therapies on quality of life. VI. Evaluate the effect of these
therapies on the balance of energy intake and energy expenditure.