Randomized Double-blind Trial of Midazolam and Loxapine in Agitated Patients
Status:
Terminated
Trial end date:
2007-10-01
Target enrollment:
Participant gender:
Summary
Neuroleptics are used since a long time in the management of severely agitated patients.
Loxapine is routinely used in our country, with, to our knowledge no severe adverse event
reported, in this indication.
However, recently, benzodiazepines have appeared interesting in agitated patients, with the
use of midazolam.
The aim of this study is to compare midazolam to loxapine in the treatment of severe agitated
patients admitted in the emergency department.