Randomized Controlled Trial of Mailed Nicotine Replacement Therapy to Canadian Smokers

Trial end date:
Target enrollment:
Participant gender:
This study will examine the efficacy of mailed distribution of free Nicotine Replacement Therapy to smokers. Telephone numbers will be randomly selected from across Canada in order to recruit adult smokers interested in completing a smoking survey and willing to be interviewed again in 8 weeks and 6 months time. Study participants will be asked about their smoking history and a hypothetical question: would they be interested in receiving the nicotine patch if this were to be provided to them free of charge? Participants expressing interest will be randomly assigned to one of two groups. One group will be offered the opportunity to actually receive a program of 5 weeks of the nicotine patch for free right away and the other group will not be offered the free nicotine patches. The proportions of smokers in the two groups who quit smoking by the 6-month interview will be compared.
Phase 4
Accepts Healthy Volunteers?
Lead Sponsor:
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)
Inclusion Criteria:

- 18 years of age and older

- Current daily smokers who smoke 10 or more cigarettes per day

- Interested in being involved in a smoking study

- Willing to be interviewed at baseline, 8 weeks and 6 months after

- Willing to provide a saliva sample for cotinine analysis at each time point

- Interest in using nicotine patch to quit smoking

- Intent to use nicotine patch within one week of receiving it

- Willing to have nicotine patch sent to their home

Exclusion Criteria:

- Have a medical condition that would would make participation medically hazardous as
determined by the list of contraindications for NRT outlined in the CPS and the NRT
package insert

- Pregnant, intending on becoming pregnant, or nursing