Overview

Randomized Controlled Trial Comparing Long and Short Duration of Antibiotic Prophylaxis for Patients Undergoing Sinus Lift Surgery

Status:
Unknown status

Trial end date:
2018-05-01

Target enrollment:

Participant gender:

Summary

The optimal use of prophylactic antibiotic therapy to prevent infection after sinus lift and augmentation surgery is unknown. This is a comparative open label interventional trial comparing a standard 7-day course of postoperative treatment with amoxicillin-clavulanate with short antibiotic treatment for up to 24 hours postoperatively. The primary study outcome is the postoperative surgical site infection in the standard versus the short treatment arms. Secondary outcomes are drug-related adverse events and Clostridium difficile infection.

Phase:

Phase 3

Details

Lead Sponsor:

Tel-Aviv Sourasky Medical Center

Treatments:

Amoxicillin
Amoxicillin-Potassium Clavulanate Combination
Anti-Bacterial Agents
Clavulanic Acid
Clavulanic Acids