Randomized Controlled Trial Comparing Irrisept Versus Normal Saline for Wound Irrigation After Posterior Spine Surgery

• Status: Not yet recruiting
• Trial end date: 2026-07-01
• Target enrollment: 0
• Participant gender: All

Summary

To compare post-operative wound complications in patients randomized to normal saline versus Irrisept solution and any other adverse reactions from the solution.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Missouri-Columbia

Criteria

Inclusion Criteria:

Presenting to the University of Missouri hospital system - including the University of Missouri Hospital and Missouri Orthopaedic Institute - with a need for isolated open posterior spine procedures using a posterior open approach.

Failed conservative treatment - rest, anti-inflammatory medications, physical therapy

>18 years old and able to provide informed consent

Exclusion Criteria:

Ongoing or suspected infection

Revisions of failed back surgeries

Documented allergy to CHG or CHG products

Pregnancy - qualitative beta hCG testing will be performed prior to enrollment

Prisoners or wards of the state

Unable to consent to research study