Overview Randomised Study to Compare the Efficacy of AZD6244 vs TMZ Status: Completed Trial end date: 2013-07-01 Target enrollment: Participant gender: Summary The primary purpose of this study is to compare the efficacy of AZD6244 (ARRY-142886) with temozolomide in patients with advanced melanoma Phase: Phase 2 Details Lead Sponsor: AstraZenecaTreatments: DacarbazineTemozolomide