Randomised Placebo-Controlled Trial of Modafinil for Cocaine Dependence

• Status: Unknown status
• Trial end date: 2007-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The study aims to evaluate the safety and efficacy of modafinil (200 mg/day) over 10 weeks plus a tailored cognitive behavioural therapy program in the treatment of cocaine dependence.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The University of New South Wales
• Collaborators: Australian Government Department of Health and Ageing; Kirketon Road Centre, Sydney Hospital; St Vincent's Hospital, Sydney
• Treatments: Armodafinil; Cocaine; Modafinil

Criteria

Inclusion Criteria:

• DSM-IV cocaine dependence diagnosis

• Cocaine positive urine sample at intake

• Regular current cocaine use (2-3 days per week)

• Aged 18 years or older

Exclusion Criteria:

• Pregnant or nursing females

• Concurrent uncontrolled physical or mental illness