Randomised Controlled Trial of Electroconvulsive Therapy (ECT) in Relapse Prevention of Depression

• Status: Completed
• Trial end date: 2012-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to determine if continuation electroconvulsive therapy (ECT) is safe and effective in relapse prevention of depression.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Örebro County Council
• Collaborator: Uppsala-Örebro Regional Research Council
• Treatments: Lithium Carbonate; Venlafaxine Hydrochloride

Criteria

Inclusion Criteria:

1. MINI-PLUS verified major depressive episode (unipolar or bipolar).

2. ECT within the last 3 weeks.

3. Either Remission defined as MADRS < 10 or

4. Response defined as MADRS < 15 combined with patient assessed CGI-I of at least much improved

Exclusion Criteria:

1. Schizophrenia or Schizoaffective disorder

2. Addiction or Dependence

3. Kidney disease that contraindicates lithium treatment

4. Vascular or heart disease that contraindicates venlafaxine treatment

5. Uncontrolled Epilepsia

6. Age less that 18

7. Pregnancy or Lactation