Overview

Ramipril for the Treatment of COVID-19

Status:
Recruiting
Trial end date:
2021-05-01
Target enrollment:
Participant gender:
Summary
In this study we propose to treat 560 patients with ramipril or placebo for 14 days. After an initial evaluation for COVID-19 status, medical history, and symptom assessment, patients will receive either 2.5 mg/day of ramipril or placebo. Patients' symptoms and study endpoints will be monitored at regular intervals. After 14 days, patients will undergo a laboratory assessment and an end-of-treatment follow-up visit at day 28. The primary endpoints of successful therapy will be improved survival, reductions in ICU admissions, and/or reductions in use of mechanical ventilator support.
Phase:
Phase 2
Details
Lead Sponsor:
University of California, San Diego
Collaborator:
Pfizer
Treatments:
Ramipril