Ramipril and Hydrochlorothiazide Alone and in Combination for the Treatment of Essential Hypertension

• Status: Completed
• Trial end date: 2007-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if there is greater blood pressure reduction using ramipril or hydrochlorothiazide alone or ramipril and hydrochlorothiazide together.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Pfizer
• Treatments: Angiotensin-Converting Enzyme Inhibitors; Hydrochlorothiazide; Ramipril

Criteria

Inclusion Criteria:

• Previously diagnosed, or newly diagnosed essential hypertension. Blood pressure must be within a minimum and maximum range prior to drug treatment.

Exclusion Criteria:

• Inability to discontinue all prior antihypertensive medications

• Heart failure

• History of stroke, myocardial infarction, or chest pain within 3 years, or an abnormal heart rhythm

• Liver or kidney disease

• Certain drugs used to treat other conditions like an enlarged prostate gland, or arthritis

• Allergy or reactions to certain medications used to treat high blood pressure

Other protocol-defined inclusion and exclusion criteria apply.