Ramipril Versus Carvedilol in Duchenne and Becker Patients
Status:
Unknown status
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
Data on preventive therapy in Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy
(BMD) affected individuals without cardiac involvement are very limited and currently lacking
regard both ACE-inhibitors and Beta-Blockers in Becker Muscular Dystrophy and for the latter
even in Duchenne Muscular Dystrophy patients. Thus, the study aim is to compare the efficacy
of carvedilol vs ramipril on myocardial tissue properties and heart function, performing CMR
and myocardial Ultrasound Tissue Characterisation analysis.