Radiosensitization of Multiple Brain Metastases Using AGuIX Gadolinium Based Nanoparticles
Status:
Completed
Trial end date:
2019-02-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. AGuIX particles
may increase the effectiveness of radiation therapy by making tumor cells more sensitive to
radiation.
PURPOSE: This first-in-man Phase I trial will study the side effects and best dose of AGuIX
when injected together with whole brain radiation therapy in treating patients with multiple
brain metastases. The effectiveness of the combination of AGuIX and radiation therapy will be
also assessed.