Radioembolization in Elderly/ Fragile Patients With mCRC
Status:
Not yet recruiting
Trial end date:
2028-10-01
Target enrollment:
Participant gender:
Summary
Radioembolization (RE) is a minimally invasive treatment with administration of radioactive
microspheres into the hepatic artery via a microcatheter. Since tumors are preferentially
supplied by the hepatic artery, most microspheres get trapped in the tumor. RE has been shown
a feasible and safe procedure for the treatment of unresectable CRC liver metastases. These
data compare favourably with the toxicity data of capecitabine plus bevacizumab, but this
should be validated in a prospective study.
The proposed study investigates the efficacy of RE as an alternative, better tolerated and
more cost-effective treatment option in elderly or frail patients compared to chronic
systemic treatment with comparable progression-free survival.