Overview

Radiation Therapy or Temozolomide in Treating Patients With Gliomas

Status:
Completed
Trial end date:
2014-05-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether radiation therapy is more effective than temozolomide in treating gliomas. PURPOSE: This randomized phase III trial is studying radiation therapy to see how well it works compared to temozolomide in treating patients with gliomas.
Phase:
Phase 3
Details
Lead Sponsor:
European Organisation for Research and Treatment of Cancer - EORTC
Collaborators:
British Medical Research Council
NCIC Clinical Trials Group
Trans Tasman Radiation Oncology Group
Trans-Tasman Radiation Oncology Group (TROG)
Treatments:
Dacarbazine
Temozolomide