Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma
Status:
Active, not recruiting
Trial end date:
2026-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Specialized
radiation therapy that delivers a high dose of radiation directly to the tumor may kill more
tumor cells and cause less damage to normal tissue. Drugs used in chemotherapy, such as
temozolomide, work in different ways to stop the growth of tumor cells, either by killing the
cells or by stopping them from dividing. It is not yet known whether radiation therapy is
more effective when given together with or without temozolomide in treating patients with
low-grade glioma.
PURPOSE: This randomized phase III trial is studying radiation therapy so see how well it
works when given together with or without temozolomide in treating patients with low-grade
glioma.