Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme
Status:
Completed
Trial end date:
2016-08-10
Target enrollment:
Participant gender:
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in
chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells,
either by killing the cells or by stopping them from dividing. Giving radiation therapy
together with temozolomide may kill more tumor cells. It is not yet known whether radiation
therapy and temozolomide are more effective than radiation therapy alone in treating
glioblastoma multiforme.
PURPOSE: This randomized phase III trial is studying radiation therapy and temozolomide to
see how well they work compared with radiation therapy alone in treating patients with newly
diagnosed glioblastoma multiforme.
Phase:
Phase 3
Details
Lead Sponsor:
Canadian Cancer Trials Group
Collaborators:
European Organisation for Research and Treatment of Cancer - EORTC Trans Tasman Radiation Oncology Group Trans-Tasman Radiation Oncology Group (TROG)