Overview

Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma

Status:
Recruiting

Trial end date:
1969-12-31

Target enrollment:

Participant gender:

Summary

Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving radiation with concomitant and adjuvant temozolomide versus radiation with adjuvant PCV is more effective in treating anaplastic glioma or low grade glioma.

Phase:

Phase 3

Details

Lead Sponsor:

Alliance for Clinical Trials in Oncology

Collaborators:

Canadian Cancer Trials Group
European Organisation for Research and Treatment Center (EORTC)
National Cancer Institute (NCI)
NCIC Clinical Trials Group

Treatments:

Dacarbazine
Procarbazine
Temozolomide
Vincristine