Radiation Therapy Combined With Chemotherapy in Treating Patients With Anaplastic Astrocytoma or Mixed Gliomas
Status:
Completed
Trial end date:
2018-05-14
Target enrollment:
Participant gender:
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in
chemotherapy, such as temozolomide, carmustine, and lomustine, use different ways to stop
tumor cells from dividing so they stop growing or die. Combining radiation therapy with
chemotherapy may kill more tumor cells.
PURPOSE: This randomized phase III trial is studying radiation therapy and temozolomide to
see how well they work compared to radiation therapy and carmustine or lomustine in treating
patients with anaplastic astrocytoma or mixed gliomas.
Phase:
Phase 3
Details
Lead Sponsor:
Radiation Therapy Oncology Group
Collaborators:
Eastern Cooperative Oncology Group National Cancer Institute (NCI) North Central Cancer Treatment Group NRG Oncology