Radiation Therapy, Chemotherapy, and Soy Isoflavones in Treating Patients With Stage IIIA-IIIB Non-Small Cell Lung Cancer
Status:
Completed
Trial end date:
2019-11-11
Target enrollment:
Participant gender:
Summary
This phase I trial studies the side effects of soy isoflavones when given together with
radiation therapy and chemotherapy in treating patients with stage IIIA-IIIB non-small cell
lung cancer. Radiation therapy uses high energy x rays to kill tumor cells. Drugs used in
chemotherapy, such as cisplatin, pemetrexed sodium, and etoposide, work in different ways to
stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Soy isoflavones may help radiation therapy, cisplatin, pemetrexed sodium, and
etoposide work better by making tumor cells more sensitive to the drug. Soy isoflavones may
also protect normal cells from the side effects of radiation therapy and chemotherapy.