Overview

Radiation Dose in Humans From Orally Administered Tc99m-Heparin

Status:
Completed
Trial end date:
2020-10-01
Target enrollment:
Participant gender:
Summary
This is a research study of a new agent used for evaluation of inflammation in the GI tract. This agent is investigational and thus is being studied to determine appropriate dosing and administration in both normal controls (i.e. people without gastrointestinal complaints) and patients with eosinophilic disease (i.e. those with an immune reaction and inflammation in their bodies with a certain cell called an eosinophil). The study will test whether the radiolabeled agent will bind to the inflammation of eosinophilic esophagitis patients because an animal model of eosinophilic esophagitis which shows the striking deposition of eosinophil granule proteins is not available.
Phase:
Early Phase 1
Details
Lead Sponsor:
University of Utah
Treatments:
Calcium heparin
Heparin