Overview

RICE: Radio-Immuno-Chemotherapy of Cancer of the Esophagus

Status:
Recruiting
Trial end date:
2024-06-01
Target enrollment:
Participant gender:
Summary
A phase II trial to evaluate safety and efficacy of adding durvalumab (MEDI4736) to standard neoadjuvant radiochemotherapy and of adjuvant durvalumab +/- tremelimumab in locally advanced esophageal adenocarcinoma and to evaluate biomarkers predictive for response to immune checkpoint inhibition
Phase:
Phase 2
Details
Lead Sponsor:
University of Cologne
Collaborator:
AstraZeneca
Treatments:
Antibodies, Monoclonal
Durvalumab
Tremelimumab