Overview

REduced Frequency ImmuNE Checkpoint Inhibition in Cancers

Status:
Not yet recruiting
Trial end date:
2025-04-01
Target enrollment:
Participant gender:
Summary
The REFINE trial aims to asses whether giving an immunotherapy drug less-often to patients with advanced cancer, results in fewer side effects whilst continuing to be an effective treatment. The question will be assessed in different tumour types by means of different cohorts within an overarching trial protocol.
Phase:
Phase 2
Details
Lead Sponsor:
University College, London
Collaborators:
Jon Moulton Charity Trust
JP Moulton Charitable Trust
Treatments:
Nivolumab
Pembrolizumab