Overview

REduCing Immunogenicity to PegloticasE (RECIPE) Study

Status:
Completed
Trial end date:
2021-03-31
Target enrollment:
Participant gender:
Summary
Pegloticase treatment for chronic refractory gout is limited by immunogenicity. The investigators propose the REduCing Immunogenicity to PegloticasE (RECIPE) trial to begin to investigate the question of whether a short course of immune modulating therapy with mycophenolate mofetil can significantly and safely attenuate immunogenicity to pegloticase and ensure patients afflicted with chronic refractory gout have better treatment outcomes and improved quality of life.
Phase:
Phase 2
Details
Lead Sponsor:
University of Alabama at Birmingham
Collaborator:
University of Michigan
Treatments:
Mycophenolate mofetil
Mycophenolic Acid