Overview

RCT of Brain Longitudinal Biomarker Study (OPT-Neuro RCT)

Status:
Active, not recruiting
Trial end date:
2025-02-28
Target enrollment:
Participant gender:
Summary
The purpose of this study is to assess which antidepressants work the best in older adults who have treatment-resistant depression (TRD), and to test whether treatment-resistant late life depression is associated with declines in memory and attention and brain structure and function.
Phase:
Phase 4
Details
Lead Sponsor:
Centre for Addiction and Mental Health
Collaborator:
National Institute of Mental Health (NIMH)
Treatments:
Aripiprazole
Bupropion
Lithium Carbonate
Nortriptyline