Overview

Quintuple Method for Treatment of Multiple Refractory Colorectal Liver Metastases

Status:
Not yet recruiting
Trial end date:
2025-03-15
Target enrollment:
Participant gender:
Summary
The aim of this study is to explore the therapeutic effect of Quintuple method in the treatment of patients with multiple and refractory liver metastases from colorectal cancer. A randomized single-arm clinical trial was conducted.The intervention group was treated with single SOX chemotherapy, SOX chemotherapy combined with cetuximab targeted therapy, SOX chemotherapy combined with low-dose cetuximab targeted therapy combined with three-drug regimen(Quintuple method), and the RECIST 1.1 solid tumor evaluation criteria were used to assess the disease.
Phase:
Phase 2
Details
Lead Sponsor:
Liaoning Tumor Hospital & Institute
Treatments:
Cetuximab
Folic Acid
Metronidazole
Oxaliplatin
Tegafur
Vitamin A