Quetiapine Induced Neuroplasticity in First-episode Schizophrenic Patients
Status:
Completed
Trial end date:
2011-03-01
Target enrollment:
Participant gender:
Summary
Aim of the study is to assess the effect of quetiapine treatment in neuroleptic naive,
first-episode schizophrenic patients on aspects of functional and structural neuroplasticity
assessed by means of transcranial magnetic stimulation and voxel-based morphometry. Main
outcome measure is a change in gray matter density under quetiapine treatment from baseline
to steady-state-treatment after 3 weeks.