Quantifying Airway Inflammation With Radiologic Tests
Status:
Completed
Trial end date:
2008-03-01
Target enrollment:
Participant gender:
Summary
In this randomized, double-blind, placebo controlled trial we used positron emission
tomography to determine if lovastatin or recombinant human activated protein C exhibit
anti-inflammatory effects in humans following intrabronchial installation of
lipopolysaccharide (LPS or endotoxin).
Phase:
Early Phase 1
Details
Lead Sponsor:
Washington University School of Medicine
Collaborator:
Barnes-Jewish Hospital
Treatments:
Dihydromevinolin Drotrecogin alfa activated L 647318 Lovastatin Protein C