Quality of Recovery Under Low or Standard Pneumoperitoneum Pressure
Status:
Not yet recruiting
Trial end date:
2022-01-15
Target enrollment:
Participant gender:
Summary
The use of low-pressure pneumoperitoneum seems to be able to reduce complications such as
postoperative pain. However, the quality of evidence for most studies evaluating this
relationship is considered low. The absence of concealment of pneumoperitoneum pressure and
the lack of description of neuromuscular blockade characteristics are the main causes of
bias. The purpose of this study will be to evaluate by means of a prospective, randomized and
double-blinded trial, the quality of recovery (QoR-15) questionnaire of patients undergoing
laparoscopic cholecystectomy under moderate neuromuscular blockade, using low
pneumoperitoneum pressure or "standard" pressure. Eighty patients submitted to laparoscopic
cholecystectomy and randomly distributed in two groups will be included: low pneumoperitoneum
pressure (10 mmHg) or "standard" pressure (14 mmHg). The value of abdominal pressure will be
kept hidden for all participants, except for the nurse responsible for the operating room.
Moderate neuromuscular blockade will be maintained according to Train-of-four count (TOFc) =
3 for all cases.