Pyronaridine/Artesunate -Ritonavir Drug Drug Interaction Study
Status:
Completed
Trial end date:
2010-09-01
Target enrollment:
Participant gender:
Summary
Pyronaridine/ artesunate (Pyramax) is an antimalarial therapy which has been demonstrated to
be a safe and effective treatment in patients with Plasmodium falciparum and vivax malaria.
This drug interaction study is intended to investigate if there is any interaction between
Pyramax and the protease inhibitor ritonavir in healthy subjects using ritonavir as a probe
substrate.