Pyridostigmine Efficacy and Safety for Treatment of Ileus After Colorectal Surgery
Status:
Not yet recruiting
Trial end date:
2023-01-01
Target enrollment:
Participant gender:
Summary
A double blind, placebo controlled, randomized control trial studying the safety and efficacy
of pyridostigmine as a rescue therapy for postoperative ileus. Patients who undergo elective
colorectal resection with or without creation of an ostomy, and subsequently develop
postoperative ileus will be eligible for enrollment. Patients will be randomized to receive
either pyridostigmine or placebo in addition to the current elements of standard of care.
Patients will also complete the pyridostigmine bromide side effects scale (PBSES) upon
enrollment and following each administration of either intervention or placebo to monitor
treatment safety and evaluate for the development of side effects.