Pupillary Reflex Measurement to Guide Intraoperative Analgesia During Laparoscopic Surgery

• Status: Completed
• Trial end date: 2018-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether analgesia guided by pupillary reflex during laparoscopic surgery is effective in opioid sparing (intraoperative remifentanil and postoperative morphine).This is a prospective, randomized, controlled study performed in two centers.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Central Hospital, Nancy, France
• Treatments: Antihypertensive Agents; Esmolol; Nicardipine; Remifentanil; Urapidil

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists status 1 to 4

• Scheduled laparoscopic surgery

• Standardized anesthesia (TCI)

• Social security affiliation

Exclusion Criteria:

• Age < 18 yrs old

• Emergency

• BMI ≥ 35 kg.m-2

• Refusal of consent

• History of ocular pathology

• Intake of: metoclopramide, droperidol, opioids or substitutive therapies

• Patient with chronic pain

• Neurologic impairments

• Neuropathic pain

• Drug or alcohol abuse