Pulmonary Gas Exchange Response to Indacaterol in COPD
Status:
Unknown status
Trial end date:
2015-11-01
Target enrollment:
Participant gender:
Summary
To evaluate the pulmonary gas exchange response to a therapeutic high dose of inhaled
indacaterol (300 mcg) in 20 outpatients with stable symptomatic COPD B and D GOLD 2011
groups.
Measurements on a single day before and after 60 and 120 minutes of indacaterol will include
arterial PO2, PaCO2 and pH. AaPO2; SaO2 (by pulse oximetry) and oxygen and carbon dioxide in
exhaled breath, systemic arterial pressure and heart rate will also be measured/calculated.
Cardiac output will be directly measured by bio-impedance.