Protracted Effect of the Ultrasound-guided Saphenous Block

• Status: Completed
• Trial end date: 2016-02-01
• Target enrollment: 0
• Participant gender: All

Summary

This study focuses on optimizing the postoperative pain treatment after major foot and ankle surgery by prolonging the duration of the ultrasound-guided saphenous block. The currently used single shot saphenous block only covers half of the pain intensive period from the saphenous territory, which results in a sharp, break-through pain requiring opioids. The hypothesis is that this protracted mixture will keep the patients free of pain without the use of opioids for the entire pain intensive period and thus increase rehabilitation and patients' satisfaction.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Aarhus
• Treatments: BB 1101; Bupivacaine; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Epinephrine; Epinephryl borate; Racepinephrine

Criteria

Inclusion Criteria:

• Elective ankle or hind foot surgery either: (1) total ankle arthroplasty, (2) ankle arthrodesis or (3) subtalar arthrodesis

• Age ≥ 18

• American Society of Anaesthesiology Classification I-III

• Informed consent both orally and in writing after the patient has fully understood the protocol and its limitations.

Exclusion Criteria:

• Communication problems or dementia

• Allergies to any medical product used in the study

• Neuropathy of the sciatic or femoral nerve prior to the operation

• Morbus Charcot-Marie-Tooth disease, diabetic neuropathy, peripheral vascular disease

• BMI > 35

• Pregnancy

• Daily use of opioids

• Coagulation disorders

• Infection at the site of injection or systemic infection