Protective Effect of N-acetylcysteine Against From Ototoxicity
Status:
Completed
Trial end date:
2011-11-01
Target enrollment:
Participant gender:
Summary
Peritonitis is currently one of the leading complications of continuous ambulatory peritoneal
dialysis (CAPD). Aminoglycosides and vancomycin are used in the treatment of CAPD peritonitis
despite their potential risk for ototoxicity. NAC is a molecule used in the treatment and
prophylaxis of many diseases related to oxidative stress. The aim of this study was to
examine whether ototoxicity due to antibiotics used in the treatment of CAPD peritonitis can
be prevented by N-acetylcysteine