Prostaglandin E2 in Migraine Suffers Without Aura.

• Status: Completed
• Trial end date: 2011-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The hypothesis of this study is that Prostaglandin E2 (PGE2) induces headache and dilatation of brain vessels in migraine patients without aura.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Troels Wienecke
• Treatments: Dinoprostone

Criteria

Inclusion Criteria:

• Patients with migraine without aura

Exclusion Criteria:

• Tension type headache more than x 3 per month

• Other forms for primary headache

• Headache 24 h before the day of the investigation

• Migraine 48 h before the day of the investigation

• Hypertension

• Hypotension

• Pregnant/nursing

• Daily intake of medication (except oral contraceptives and migraine rescue medicine during migraine attack)

• Cardiovascular or central nervous system (CNS) disease

• Drug/alcohol abuse

• Psychiatric disease

• Asthma or any other lung diseases