Prospective Trial of Metformin - Chemoprevention Role
Status:
Withdrawn
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The goal of this clinical research study is to learn if metformin extended release (ER) can
prevent colonic adenomas from becoming cancerous. Metformin ER will be compared to a placebo.
Metformin ER is designed to block a protein in tumor cells that is important in tumor growth
and blood vessel development. This may cause cell death or reduce the spread of the disease.
A placebo is not a drug. It looks like the study drug but is not designed to treat any
disease or illness. It is designed to be compared with a study drug to learn if the study
drug has any real effect.