Prospective Study to Prevent Puerperal / Perinatal Infection in Vaginal Delivery

• Status: Not yet recruiting
• Trial end date: 2026-05-31
• Target enrollment: 0
• Participant gender: Female

Summary

This is a multi-center, randomized, controlled trial study to find whether use of chlorhexidine-alcohol or povidone-iodine for pre-vaginal delivery skin prep is superior to reduce postpartum infection in pregnant women with vaginal delivery. The primary outcome is the episiotomy site infection.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Seoul National University Hospital
• Treatments: Chlorhexidine; Chlorhexidine gluconate; Iodine; Povidone; Povidone-Iodine

Criteria

Inclusion Criteria:

• Women with singleton pregnancy

• Women who will undergo vaginal delivery after 37+0/7 weeks of gestation

Exclusion Criteria:

• Women who are allergy to chlorhexidine, alcohol, iodine, or shellfish

• Women with any infection at perineum (before vaginal delivery)