Overview

Prospective Randomized Study: Assessment of PRF Efficacy in Prevention of Jaw Osteonecrosis After Tooth Extraction

Status:
Unknown status
Trial end date:
2017-01-01
Target enrollment:
0
Participant gender:
All
Summary
This prospective study will include patients taking or having taken bisphosphonates and needing dental extractions. The aim of this study is to validate the contribution of PRF (Platelet Rich Fibrin) in tooth extraction sites. In the test group (PRF) and in the control group (no PRF), we use the same atraumatic extraction protocol associated with the same antibiotic procedure.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Treatments:
Amoxicillin
Amoxicillin-Potassium Clavulanate Combination
Anti-Bacterial Agents
Antibiotics, Antitubercular
Clavulanic Acid
Clavulanic Acids
Diphosphonates
Criteria
Inclusion Criteria:

- patients taking bisphosphonates whatever the indication, the type, the administration
and the duration of treatment (we include patients taking or having taken
bisphosphonates, even several years ago)

- And who need tooth extraction (not recoverable in conservative dentistry and
symptomatic tooth: dental and periodontal infections, symptomatic traumatic tooth
fracture).

Exclusion Criteria:

- pregnant women

- younger than 50 years old

- jaw's radiotherapy

- history of jaw osteonecrosis

- jaw metastasis from an other cancer