Prospective Multicenter Doubleblind Randomized Study of NXL104/Ceftazidime + Metronidazole vs. Meropenem in Treatment of Complicated Intra-abdominal Infections

• Status: Completed
• Trial end date: 2009-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether NXL104 plus ceftazidime is effective in the treatment of complicated intra-abdominal infections as compared to a comparator group.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Novexel Inc; Pfizer
• Treatments: Avibactam; Ceftazidime; Meropenem; Metronidazole; Thienamycins

Criteria

Inclusion Criteria:

• complicated intra-abdominal infections

Exclusion Criteria:

• infections limited to hollow viscus

• ischemic bowel disease without perforation

• acute suppurative cholangitis

• acute necrotizing pancreatitis

• pts to undergo stated abdominal repair, open abdomen technique or marsupialization

• Apache II >25