Overview

Prospective Comparison of Metolazone Versus Chlorothiazide for Acute Decompensated Heart Failure With Diuretic Resistance

Status:
Terminated
Trial end date:
2021-01-01
Target enrollment:
Participant gender:
Summary
The primary objective of the study is to compare efficacy of metolazone and chlorothiazide as add-on therapy in patients refractory to loop diuretics with heart failure with a reduced ejection fraction (HFrEF). This will be a single-center randomized pilot study.
Phase:
Phase 4
Details
Lead Sponsor:
University of Virginia
Treatments:
Chlorothiazide
Diuretics
Metolazone