Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

To compare the effectiveness of standard treatment with parenteral ampicillin and oral amoxicillin compared to initial daily therapy with ceftriaxone followed by 3 times weekly suppressive treatment for salmonella infections in AIDS patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Southern California
• Treatments: Amoxicillin; Ampicillin; Ceftriaxone

Criteria

Exclusion Criteria

Co-existing Condition:

Patients with the following are excluded:

• Type I hypersensitivity to beta-lactam antibiotics.

• Not expected to survive 12 weeks.

• In a coma or with other central nervous system (CNS) impairment.

Patients with the following are excluded:

• Type I hypersensitivity to beta-lactam antibiotics.

• Not expected to survive 12 weeks.

• In a coma or with other central nervous system (CNS) impairment.

Prior Medication:

Excluded within 48 hours of study entry:

• Treatment with an antibiotic active in vitro against Salmonella.

HIV infection, AIDS, or AIDS related complex (ARC).

• Salmonella bacteremia or positive stool culture in patient with 3 or more stools per day.