Prospective Comparative Study of the Efficacy of Common Antipyretic Treatments in Febrile Children

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This study will examine in detail the immediate effects of three common treatments given to children with fevers to lower their temperature. Each child will be given either ibuprofen, acetaminophen, or a combination, and their temperature monitored at five-minute intervals. The temperature-lowering effects of each treatment will be compared to evaluate which is most effective.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lawson Health Research Institute
• Treatments: Acetaminophen; Antipyretics; Ibuprofen

Criteria

Inclusion Criteria:

• fever between 38 and 41 Celsius (inclusive) on presentation to ER

• assessment by treating physician that patient requires antipyretic treatment

Exclusion Criteria:

• known allergy or hypersensitivity to either study medication

• received any antipyretic medication in past eight hours

• patient requires admission to hospital

• co-morbidities indicating increased risk of complication

• assessment by treating physician that patient is medically unsuitable for the study