Overview

Propranolol With Standard Chemoradiation for Esophageal Adenocarcinoma

Status:
Recruiting
Trial end date:
2024-04-01
Target enrollment:
Participant gender:
Summary
This phase II trial studies the side effects and best dose of propranolol when administered concurrently with SOC neoadjuvant CRT in patients with esophageal carcinoma, with a safety lead-in and dose expansion cohort. Patients who are already on β-blockers will receive standard of care CRT and will be considered separately as a single arm prospective cohort
Phase:
Phase 2
Details
Lead Sponsor:
Roswell Park Cancer Institute
Treatments:
Carboplatin
Paclitaxel
Propranolol